Nexium 24HR Once Daily Dosing Tablets provide lasting relief from frequent heartburn and acid reflux.
Nexium 24HR 20mg esomeprazole tablets are for the lasting symptomatic relief of frequent heartburn, acid regurgitation and other symptoms associated with gastro-oesophageal reflux
Carefully read the enclosed Consumer Medicine Information before use.
AUST R NUMBER:231439
Lactose
INGREDIENTS:Each tablet contains: Esomeprazole 20mg (as Magnesium Trihydrate).
Do not use:- for children under 18 years of age.- if allergic to esomeprazole.- if allergic to any other proton pump inhibitor (omeprazole, rabeprazole, lansoprazole, pantoprazole).- if you are taking antiretroviral medicines, such as atazanavir.- if you are taking cilostazol a medicine used to treat pain and/or cramping in the lower leg (or arms) due to inadequate blood flow to the muscles.- if you are breastfeeding or intend to breastfeed.- -f you are experiencing weight loss, persistent regurgitation of food or vomiting, difficulty swallowing or symptoms of gastro-intestinal bleeding, except on medical advice- if you are pregnant or intend to become pregnant except on the advice of a doctor or pharmacist- if the expiry date printed on the pack has passed. Ask your pharmacist or doctor before use if you:- have or ever have had serious liver disease.- are taking digoxin (a medicine used to treat heart problems).- are taking ketoconazole (a medicine used to treat fungal infections)- are taking clopidogrel or warfarin (medicines used to stop the blood clotting)- are taking other medicines regularlyThis preparation is for the relief of minor and temporary ailments and should be used strictly as directed. Do not use for any purpose other than what is specified on the pack, except on doctor's advice. Keep to recommended dose. If an overdose is taken or suspected telephone your doctor or the Poisons Information Centre (Australia 13 11 26, or New Zealand 0800 764 766) or go to the Accident and Emergency department at your nearest hospital. Tell your pharmacist or doctor if you do not feel well, if new or additional symptoms occur while you are taking Nexium 24HR Once Daily Dosing.
ONLINE MANDATORY STATEMENT:Always read the label and follow the directions for use.
Puerto Rico, US
Approversy PillsName | Id | Chemical Class | Strength | Type |
---|---|---|---|---|
Nexium 24HR | Esomeprazole | Magnesium Trihydrate | 20mg, 40mg | |
In a move that could be called the "outshine" of the heartburn treatment, the New York-based Nexium maker, AstraZeneca, announced today it has entered into an agreement with Pharmacia, the world's largest generic drug maker, to sell the company's rights to a generic version of the drug, esomeprazole magnesium.
The deal follows Pfizer's launch of esomeprazole magnesium for gastroesophageal reflux disease, a new generic alternative to the heartburn medication Prilosec. Both AstraZeneca and Pharmacia are expected to announce their respective settlements.
Pharmacia will pay $1.3 billion to settle generic drug claims by AstraZeneca, up from $1.4 billion in 2011. The company will continue to sell its drug, esomeprazole, in about 10,000 cases, which would cover approximately 40 percent of the generic version.
"The settlement provides pharmacologic alternatives to the generic Prilosec, which are still being researched and are not expected to be launched until at least next year," said Charles A. Gilmartin, Ph. D., president and chief executive officer of Pharmacia. "The company is disappointed with the agreement, but we will continue to pursue its own research and development efforts."
Pharmacia is the market leader in the anti-bacterial, anti-fungal, and gastroesophageal-allergy indications for esomeprazole magnesium, which is manufactured by AstraZeneca. In 2003, AstraZeneca filed a $10.7 billion U. S. settlement, with a total value of approximately $3.3 billion, with Pharmacia paying $3 billion in settlements, and the company has since received a payment of $1.4 billion to pay off the patent on the drug.
Pharmacia will continue to produce and market the drug and sell its generic form, esomeprazole, in about 10,000 cases, which would cover approximately 40 percent of the generic version. The company has already received a payment of $1.4 billion to pay for the generic version of the drug, which would cover about 40 percent of the generic esomeprazole magnesium.
Pharmacia's agreement with Pharmacia will help to offset a loss of approximately $1.3 billion from the U. settlement. The company is also seeking to replace the company's current generic product, esomeprazole magnesium, with a new product in the same class of products as the branded drug Nexium.
In a statement to Bloomberg, the company said: "The company's commitment to its U. patent on esomeprazole magnesium will allow pharmacologic alternatives to its Prilosec to continue to market in the U. market."
Last year, AstraZeneca filed a U. patent on the active ingredient in Nexium for esomeprazole magnesium. The patent was intended to allow the generic drug to be marketed in the U. by Pharmacia.
The settlement will not impact Nexium's other patents, which are already in litigation with AstraZeneca. However, the company's U. patent on the drug, which is scheduled to expire at the end of the year, will expire at the end of the year in February 2006.
The company is also exploring other potential drug products, including the heartburn-drug omeprazole, which is currently in an international patent on the drug and is awaiting a decision.
In a statement to Bloomberg, AstraZeneca said: "Our U. patent on the generic esomeprazole magnesium and our Nexium-branded heartburn-acid-dilating omeprazole are for the treatment of gastroesophageal reflux disease (GERD), the most common type of heartburn. These products have a significant impact on patients' health and the lives of their caregivers, which can be life-threatening."
The U. patent on Nexium, which expires in March, is scheduled to expire at the end of the year in May 2006.
The company is also considering a new generic version of its heartburn treatment Prilosec, known as Prilosec-30, to compete with the company's branded drug, Prilosec 40, to replace Nexium.
In a statement to Bloomberg, the company said: "We are pleased to have entered into a new agreement with Pharmacia, which provides the company with the additional flexibility to pursue its own research and development and licensing opportunities.
Nexium 24HR 20mg esomeprazole 20 Capsules (20 Capsules)is a proton pump inhibitor (PPI) used to treat reflux disease (such as heartburn, acid reflux, and ulcers) and other conditions caused by stomach acid. Nexium is also used to treat gastroesophageal reflux (GERD) in people who have erosive reflux disease (such as GERD associated with ulcers). This medication comes in a gel form, and you will need a prescription to buy Nexium online. It is not recommended to buy medicine over the counter, especially if you live in a country where this medicine is widely available. Nexium is known for its long-lasting effects, which last for up to 4 hours. You should notice that you get a quick onset of action from taking this medicine. For more information, visit our website.
Please read the enclosed leaflet carefully before taking this medicine. It states:
Nexium is a brand name for esomeprazole, which is used to treat certain infections caused by bacteria. It is commonly used for osteomyelitis (infection of tendons, muscles, and muscles around the tendons) and lumbago (a pain condition) in women. Nexium is commonly used to treat frequent pelvic pain, whooping cough (which is a symptom of meningitis), recurrent bacterial sinus infections, and infections in the stomach or intestines.
In addition to treating osteomyelitis and lumbago, other conditions may also be treated with Nexium. These medications may include aminoglycoside amylose andisure code, anti-diarrhea, antacids, methotrexate, pain relievers, non-steroidal anti-inflammatory drugs, probiotics, oral contraceptives, and oral contraceptives.
Nexium initially was rated as the #1 antibiotics in the world, followed by Amoxicillin and Clavulanic acid. In the second quarter of 2020, the brand saw significant growth driven by increasing demand for effective treatments such as Nexium 24, due to the increasing prevalence of bacterial infections in the country.
In Q4 of 2020, Nexium brand saw major growth due to an estimated 12.1 billion prescriptions made by pharmacies in the US, and the brand was also the #1 prescriber at bacterial pain treatment and inflammation relief clinics in the US. Nexium remains on the leading list of top-100 antibiotics for treating bacterial infections, with a primary market size of $3.8B in the US in terms of prescriptions made in 2019. This growth is driven by increasing healthcare needs such as Nexium’s adoption of an aminoglycoside prescription form and Clavulanic acid’s increasing role in treating bacterial infections.
Nexium is primarily indicated for the treatment of osteomyelitis (infection of tendons and/or ligaments) and frequent pelvic pain, which is a symptom of meningitis caused by bacterial infections. It is also used to treat various other conditions, such as lumbago (a pain condition) in women, and other conditions caused by inflammation in the spinal column.
Key Info
Warnings
If you are pregnant, planning to become pregnant, or breastfeeding, be careful using this medicine.
The rising numbers of infections in the USA and worldwide are an expected increase, as many people seek treatment for bacterial infections at an early age. The global burden of bacterial infections is estimated at $1.6T$2.1G, with an estimated prevalence of 10.8% in women and 6.7% in men. The prevalence of bacterial infections can reach 15.7% in immunocompromised people, and up to 25.4% in those with bacterial infection in the general population. As a result, the number of people afflicted with bacterial infections is increasing worldwide.